NIRII-HDs fluorescent dyes (Figure 1), developed by the Zhang Xiaobing-Yuan Lin research group, are designed for near-infrared II (NIR-II) region imaging. Compared to near-infrared I (NIR-I) and visible light, NIR-II dyes provide deeper tissue penetration and lower spontaneous background fluorescence, making them highly effective for in vivo imaging applications. These...
13
Dec
Two-photon imaging is a powerful technique in biomedical research and clinical diagnostics, offering deeper tissue penetration and reduced photodamage. The most commonly used two-photon dyes are electron donor-acceptor (D–A) type molecules, but their application is often hindered by solvation quenching effects, leading to reduced fluorescence efficiency. To overcome this challenge,...
13
Dec
The TPQL-1 and TPQL-2 fluorescent dyes, developed by the Zhang Xiaobing-Yuan Lin research group at Hunan University, are innovative two-photon dyes designed through a single-atom substitution and electron acceptor combination strategy based on the 6-ethyl-2-dimethylaminonaphthalene (acedan) structure (Figure 1). [1] In recent years, two-photon fluorescent dye imaging has gained widespread...
13
Dec
The Zhang Xiaobing-Yuan Lin research group at Hunan University has developed a novel single-benzene-based fluorescent dye (SBFs) (Figure 1). This dye offers universal emission wavelength tunability, covering the entire visible spectrum in both solutions and solid states [1]. By overcoming the strong intramolecular and intermolecular hydrogen bonding limitations of most...
12
Dec
DQF Fluorescent Dye – A Rhodamine-Based Dye with Large Stokes Shift Organic small-molecule fluorescent dyes have been widely applied in functional molecular labeling and detection, offering real-time, in-situ visualization for various biomedical research applications. However, most commonly used fluorescent dyes—such as fluorescein, rhodamine, oxazine, and cyanine—suffer from small Stokes shifts...
12
Dec
The Zhang Xiaobing-Yuan Lin research group at Hunan University has developed a new class of fluorescent dyes with high brightness, excellent photostability, and large Stokes shift—YueLu dyes (YLs). These dyes offer superior performance in protein labeling and super-resolution imaging, making them ideal for high signal-to-noise ratio protein visualization. A key...
