NIRII-HDs fluorescent dyes (Figure 1), developed by the Zhang Xiaobing-Yuan Lin research group, are designed for near-infrared II (NIR-II) region imaging. Compared to near-infrared I (NIR-I) and visible light, NIR-II dyes provide deeper tissue penetration and lower spontaneous background fluorescence, making them highly effective for in vivo imaging applications.

These dyes are particularly suitable for "always bright" imaging, allowing high-resolution visualization of lymph nodes and liver tissue.

Key Advantages of NIRII-HDs Fluorescent Dyes:

• Excellent stability for long-term imaging
• High signal-to-noise ratio for superior imaging clarity

Figure 1   NIRII-HDs Fluorescent dyes [1][1][1].

Professor Yuan Lin is a professor and doctoral supervisor at the School of Chemistry and Chemical Engineering, Hunan University and the State Key Laboratory of Chemical Biosensing and Metrology.Currently, he has published more than 100 papers in international academic journals, with a total citation of more than 12,000 times, and an h-index of 58.Among them, the first or corresponding author from 2012 to presentJ. Am. Chem. Soc.（10 articles）、 Nat. Commun.（1 articles）、 Angew. Chem. Int. Ed.（10 articles）、CCS Chem.（1 articles）、Chem. Sci.（4 articles）、Anal. Chem.（10 articles）、Adv. Funct. Mater、BiomaterialsPublished more than 70 papers in journals and other journals. Mainly engaged in research on small molecule fluorescent probes and their applications.

Product list

Fluorescent dye

1

Product name：
NIRII-HD1, 95%
CAS：N/A
Item number：9332526
Fluorescence properties：λex 792 nm; λem 880/940 nm

2

Product name：
NIRII-HD2, 95%
CAS：N/A
Item number：9332527
Fluorescence properties：λex 806 nm; λem 942 nm

3

Product name：
NIRII-HD3, 95%
CAS：N/A
Item number：9332528
Fluorescence properties：λex 802 nm; λem 886/943 nm

4

Product name：
NIRII-HD4, 95%
CAS：N/A
Item number：9332529
Fluorescence properties：λex 837 nm; λem 886/944 nm

5

Product name：
NIRII-HD5, 95%
CAS：N/A
Item number：9332530
Fluorescence properties：λex 854 nm; λem 895/936 nm

Fluorescent probe

1

Product name：
NIRII-HD5-GSH, 95%
CAS：N/A
Item number：9332531
GSH activated probe

2

Product name：
NIRII-HD5-ONOO^-, 95%
CAS：N/A
Item number：9332568
ONOO-activated probe

References

1. Zuojia Qin. et al. NIRII-HDs: A Versatile Platform for Developing Activatable NIR-II Fluorogenic Probes for Reliable In Vivo Analyte Sensing. Angewandte Chemie International Edition. 2022.