1. High brightness and high photostability protein labeling dyes—YueLu dyes (YLs) Has higher brightness (66400 M-1 cm-1 VS 32500 M-1 cm-1);Larger Stokes shift (52 nm VS 27 nm);Higher photostability (can acquire 5 times the number of frames compared to traditional probes when reduced to half the initial brightness);Probes constructed based...
16
Dec
ATP (adenosine triphosphate) is the main source of energy for cellular activities. In mitochondria, ATP causes irreversible changes in mitochondrial function through a series of chemical and biosynthetic processes (ie, oxidative phosphorylation), leading to the occurrence of many diseases such as ischemia, Parkinson's disease, and malignant tumors. Therefore, in order...
13
Dec
NIRII-HDs are a type of fluorescent dye developed by the Zhang Xiaobing-Yuan Lin team for imaging in the near-infrared II region (Figure 1). Compared with the near-infrared I region and visible light, they have deeper penetration depth and lower spontaneous background fluorescence. This type of dye can be used for...
13
Dec
Two-photon imaging is an emerging tool for biomedical research and clinical diagnostics. Electron donor-acceptor (D–A) type molecules are the most widely used two-photon scaffolds. However, the application of these dyes is limited due to the solvation quenching effect. The research group of Zhang Xiaobing-Yuan Lin of Hunan University proposed a...
13
Dec
The TPQL-1 and TPQL-2 fluorescent dyes developed by the Zhang Xiaobing-Yuan Lin research group of Hunan University were developed on the 6-ethyl-2-dimethylaminonaphthalene (acedan) structure through a single atom substitution and electron acceptor combination strategy. of new two-photon dyes (Figure 1). [1] Figure 1 TPQLs Fluorescent dyes [1] Two-photon fluorescent dye...
13
Dec
The Zhang Xiaobing-Yuan Lin research group of Hunan University developed a new fluorescent dye based on single benzene-SBFs fluorescent dye (Figure 1). The dye shows universal emission wavelength tunability, covering the entire visible light spectrum of solutions and solids. . [1] Figure 1 Rational engineering principle of single-benzene fluorophore (SB-Fluor).[1] ...
