Imaging technology based on organic small molecule fluorescent dyes has been widely used in functional molecular labeling and detection as an intuitive and in-situ visual observation technology.

However, the Stokes shift of most common fluorescent dyes (such as fluorescein, rhodamine, oxazine, and cyanine) is very small (generally <30 nm), resulting in low signal-to-noise ratio and severe fluorescence self-quenching during imaging. phenomenon, limiting its application in biological imaging.

The Zhang Xiaobing-Yuan Lin research group of Hunan University proposed a general strategy to increase the Stokes displacement of conventional fluorescent dyes - Alternating Vibronic Structures (vibration structures), and successfully synthesized rhodamine-type fluorescent dyes - DQF fluorescent dyes: DQF-560, DQF-565, DQF-584 (Figure 1) [1][1][1][1]

 Professor Yuan Lin is a professor and doctoral supervisor at the School of Chemistry and Chemical Engineering, Hunan University and the State Key Laboratory of Chemical Biosensing and Metrology.Currently, he has published more than 100 papers in international academic journals, with a total citation of more than 12,000 times, and an h-index of 58.Among them, the first or corresponding author from 2012 to presentJ. Am. Chem. Soc.（10 articles）、 Nat. Commun.（1 articles）、 Angew. Chem. Int. Ed.（10 articles）、CCS Chem.（1 articles）、Chem. Sci.（4 articles）、Anal. Chem.（10 articles）、Adv. Funct. Mater、BiomaterialsPublished more than 70 papers in journals and other journals. Mainly engaged in research on small molecule fluorescent probes and their applications.

Product list

Product name：
DQF-560, 95%
CAS：N/A
Item number：9332535
Fluorescence properties：λex 560 nm; λem 640 nm

Product name：
DQF-565, 95%
CAS：N/A
Item number：9332536
Fluorescence properties：λex 565 nm; λem 648 nm

Product name：
DQF-584, 95%
CAS：N/A
Item number：9332537
Fluorescence properties：λex 584 nm; λem 660 nm

References

1. J. Am. Chem. Soc. 2018, 140, 24, 7716–7722.