The study of protein phosphorylation (Figure 1) is called phosphoproteomics and is one of the important post-translational modification (PTM) methods in protein research, which mainly occurs on serine, threonine and tyrosine residues. This kind of PTM plays an important role in almost all cell signal transduction pathways, and at least...

According to statistics, more than two-thirds of human proteins can be phosphorylated. The huge signaling network composed of these phosphorylation sites provides important information for people to evaluate the physiological status of cells, identify disease markers, and discover drug targets. Therefore, phosphoproteomics is a very important direction in current protein...

The traditional way of connecting nucleic acids and antibodies mainly relies on the modification and reconnection of chemical coupling agents, such as azidating the sugar chain at the Fc end of the antibody, and then performing a coupling reaction with the DBCO-modified nucleic acid at the 5' end to complete...

In 2016, Professor Hong Xuechuan of Wuhan University published an article in the journal Nature Materials [1], successfully synthesizing for the first time a near-infrared fluorescence II region that can be used to label a variety of biomolecules and can be metabolized by organisms ( NIR-II) small molecule dye -...

Biochemical Diagnosis: A Key to Accurate Medical Testing Biochemical diagnosis involves enzyme reactions or antigen-antibody interactions, primarily used to measure biochemical indicators, body function markers, and various proteins like enzymes, sugars, lipids, non-protein nitrogen, and inorganic elements. This method is essential in detecting and monitoring various medical conditions. As the...

Contact lenses, also known as corneal contact lenses, are ophthalmic repair equipment used for vision correction, beauty, treatment, etc. They are usually made from silicone hydrogel, water and polymers (methacrylates).The development and manufacturing of contact lenses relies on new high-quality monomers, polymers and other reagents. Monomer selection can affect contact...