Photodynamic therapy (PDT) combines photosensitive drugs with laser activation to treat cancer effectively. Metal-based photosensitizers like tin, lutetium, palladium, and ruthenium compounds have already entered clinical trials or received approval for PDT applications. However, conventional PDT mechanisms heavily depend on oxygen, limiting their effectiveness in hypoxic cancer environments. Developing innovative...
More than 170 million people worldwide are infected with hepatitis C virus (HCV), a single-stranded positive-strand RNA virus. Once the human body is infected, it is very likely to develop diseases such as chronic hepatitis, cirrhosis and even liver cancer. Currently, the commonly used methods for detecting HCV infection in...
Small molecule cyanine is a type of strong absorbing ligand with red or near-red light, which can red-shift the absorption intensity of molecules. It has important applications in the fields of synthetic ligands for metal complexes and intermediates for the synthesis of molecular probes. In addition, cyanine...
Human serum albumin (HSA) is a protein in human plasma. HSA concentration in the blood or urinary system is a reliable indicator of various diseases such as kidney disease, hypoalbuminemia, etc.The presence of excess HSA in the urine can lead to microalbuminuria, an early marker of cardiovascular disease and kidney...
Triptycene and its derivatives are a class of compounds with a unique three-dimensional rigid structure and are widely used in many fields such as molecular machines, materials chemistry, and supramolecular chemistry [1]. Researcher Chen Chuanfeng from the Institute of Chemistry, Chinese Academy of Sciences, successfully synthesized a new host molecule...
Triptycene is a molecule with a unique three-dimensional rigid structure composed of three benzene rings (Figure 1). The angles between the three benzene rings are all 120°, forming three open electron-rich cavities. Because its structure resembles a medieval triptych, it is called triptylene. In recent years, its unique structural characteristics...