FM Series Fluorescent Dyes for High-Specificity Cell Membrane Labeling and Neuronal Tracking The FM series fluorescent dyes, including FM 1-43, FM 2-10, FM 5-95, and FM 4-64, are lipophilic styrene-based dyes known for their non-toxic nature and specific application in labeling living cell membranes. These dyes are especially effective in...

What is Chromatography? Chromatography is a fundamental technique in analytical chemistry used to separate the various components of a mixture. Imagine a container filled with different colored dyes. Separating these dyes manually is a complex task, but chromatography provides an elegant solution, similar to a sorting machine that uses the...

G-quadruplex (G4) fluorescent probes provide ideas for broadening viromics research on functional nucleic acids and developing new HCV infection detection. However, the traditional G4 dye has poor ability to cross cell membranes and is difficult to be directly used for live cell imaging.Hunan University's Nie Zhou team developed a new...

More than 170 million people worldwide are infected with hepatitis C virus (HCV), a single-stranded positive-strand RNA virus. Once the human body is infected, it is very likely to develop diseases such as chronic hepatitis, cirrhosis and even liver cancer. Currently, the commonly used methods for detecting HCV infection in...

The basic building blocks of biomimetic homopolypeptides are protected or unprotected glutamic acid or lysine residues, which are obtained through ring-opening polymerization of cyclic amino acid anhydrides. They can be used in the field of biomedicine as drug delivery, gene delivery carriers or degradable biomimetic medical materials [1-2]. They can...

Click Chemistry is a synthesis concept proposed by Sharpless, a Nobel Prize winner in chemistry from the United States, in 2001 [1]. Among them, the main and classic click chemical reaction is the Cu(I)-catalyzed azide-alkynyl Husigen cycloaddition reaction (CuAAC). This reaction has the advantages of high yield, few side reactions,...