Organometallic chemistry, which examines the synthesis, structure, reactions, properties, and applications of metal-organic compounds, plays a pivotal role in advancing human society. Metal-organic compounds consist of a central metal atom surrounded by ligands, forming stable complexes with unique properties. Among these, Carbolong Complexes stand out as an innovative class of...

The Zhang Xiaobing-Yuan Lin research group has developed an extensive range of groundbreaking fluorescent dyes, each optimized for specific scientific and biomedical applications. These advanced dyes offer high brightness, excellent photostability, and a wide range of functionalities, catering to modern imaging and labeling needs.   1. High Brightness and Photostability Protein...

The Zhang Xiaobing-Yuan Lin research group at Hunan University has developed a series of high-performance fluorescent dyes, each offering unique advantages for biological imaging, disease detection, and advanced photophysical applications. These dyes exhibit superior brightness, photostability, spectral range, and functional versatility, making them valuable tools for researchers.     1....

Adenosine triphosphate (ATP) is the primary energy carrier in cellular activities. In mitochondria, ATP drives essential biochemical and biosynthetic processes, such as oxidative phosphorylation, which can significantly impact mitochondrial function. Abnormal ATP metabolism is linked to several severe diseases, including ischemia, Parkinson’s disease, and malignant tumors. To better understand ATP’s...

NIRII-HDs fluorescent dyes (Figure 1), developed by the Zhang Xiaobing-Yuan Lin research group, are designed for near-infrared II (NIR-II) region imaging. Compared to near-infrared I (NIR-I) and visible light, NIR-II dyes provide deeper tissue penetration and lower spontaneous background fluorescence, making them highly effective for in vivo imaging applications. These...

Two-photon imaging is a powerful technique in biomedical research and clinical diagnostics, offering deeper tissue penetration and reduced photodamage. The most commonly used two-photon dyes are electron donor-acceptor (D–A) type molecules, but their application is often hindered by solvation quenching effects, leading to reduced fluorescence efficiency. To overcome this challenge,...