Fluorine is a vital non-metal element widely used in pharmaceuticals and agrochemicals. Due to its unique electronegativity, electronic effects, and steric hindrance, fluorine atoms are often introduced into drug molecules to enhance metabolic stability, permeability, and bioavailability. Over 20% of commercially available drugs and pesticides contain one or more fluorine...

Achieving specificity in catalytic reactions by mimicking the active sites and substrate-binding cavities of enzymes is a significant scientific challenge. Professor Fang Yu's research group at Hunan University has developed an innovative supramolecular photocatalytic material, PCC-6-M, based on phenothiazine and octahedral porous coordination cages. This material enables the regulation of...

The research group led by Professor Fang Yu at Hunan University has successfully developed a novel catalyst, PCC@THF-OOH, which achieves light-dark catalytic coupling. This breakthrough is based on a phenothiazine-based octahedral porous coordination cage (PCC-6-Zn), where the zinc metal center selectively generates singlet oxygen for oxidation reactions under light conditions...

Trifluoromethyldiazomethane (CF₃CHN₂) is a crucial precursor for introducing trifluoromethyl groups into organic molecules, widely applied in organic synthesis. Despite its importance, traditional production methods present significant challenges in storage, safety, and handling risks (see Figure 1). To solve these issues, Professor Bi Xihe’s research group at the School of Chemistry,...

Carboron is a novel chain polyacetylenic compound exclusively developed by Professor Xia Haiping’s research group at Xiamen University (Figure 1). This discovery marks a significant advancement in the synthesis of metallopentynes and metallopentenes, providing a one-pot synthesis method that enhances efficiency and expands application potential. Figure 1. General structural formula...

In organic experiments, rotors, columns, and plates are essential tools — but when it comes to microscopic liquid mixing, traditional rotors fall short. The innovative magnetic nanostirr, developed by Professor Chen Hongyu’s research team at Westlake University, solves this challenge by enabling efficient stirring in confined spaces like microdroplets and...