The Zhang Xiaobing-Yuan Lin research group at Hunan University has developed a series of high-performance fluorescent dyes, each offering unique advantages for biological imaging, disease detection, and advanced photophysical applications. These dyes exhibit superior brightness, photostability, spectral range, and functional versatility, making them valuable tools for researchers.
1. YueLu Dyes (YLs) – High Brightness & Photostability for Protein Labeling
YL dyes provide exceptional fluorescence performance for protein labeling and super-resolution imaging.
- Higher brightness: 66,400 M⁻¹ cm⁻¹ vs. 32,500 M⁻¹ cm⁻¹
- Larger Stokes shift: 52 nm vs. 27 nm
- Superior photostability: Enables five times more imaging frames compared to traditional probes before reaching half the initial brightness
These properties allow long-term, high-resolution imaging of labeled proteins.
| Product name | CAS | Item number |
|---|---|---|
| YL578, 95% | / | 9332511 |
| YL578-COOH, 90% | / | 9332513 |
| YL578-CF3, 90% | / | 9332514 |
| YL578-NHS, 90% | / | 9332512 |
| YL578-CF3-Halo, 95% | / | 9332517 |
| YL578-Halo, 95% | / | 9332516 |
| YL578-COOH-NHS, 90% | / | 9332515 |
2. Near-Infrared Fluorescent Dyes – Huda (HD) & Changsha (CS) Dyes
HD and CS dyes feature multiple modification sites, enabling the design of targeted fluorescent probes for specific biological structures.
- Can be modified with targeting groups to detect active biomolecules in vivo
- Effective for monitoring disease-related organ damage
- Provides high-quality imaging with deep tissue penetration
| Product name | CAS | Item number |
|---|---|---|
| HD-1, 95% | 1630289-16-5 | 9332538 |
| HD-2, 95% | 2222417-65-2 | 9332539 |
| HD-3, 95% | / | 9332540 |
| HD-4, 95% | 2216759-63-4 | 9332541 |
| HD-5, 95% | / | 346037 |
| HD-6, 95% | / | 9332542 |
| CS-1, 95% | 1374637-02-1 | 9332543 |
| CS-2, 95% | 1451145-42-8 | 9332544 |
3. Rh6G-ACFPN Fluorescent Probe – Real-Time ATP Monitoring
Designed for ATP quantification in living cells, this probe offers:
- High selectivity and sensitivity
- Optimized dissociation constant (4.65 mM), ideal for mitochondrial ATP monitoring (3–10 mM)
- Reversible response, allowing dynamic ATP level tracking
2 MG
4. NIRII-HDs Fluorescent Dyes – High Stability & Signal-to-Noise Ratio
NIRII-HDs are developed for near-infrared II (NIR-II) bioimaging, offering advantages over traditional NIR-I and visible-light imaging.
- Deeper penetration depth with lower background fluorescence
- Ideal for lymph node and liver imaging in vivo
- High signal-to-noise ratio for clear imaging results
| Product name | CAS | Item number |
|---|---|---|
| NIRII-HD1, 95% | / | 9332526 |
| NIRII-HD2, 95% | / | 9332527 |
| NIRII-HD3, 95% | / | 9332528 |
| NIRII-HD4, 95% | / | 9332529 |
| NIRII-HD5, 95% | / | 9332530 |
5. Functionalized TPCs Fluorescent Dyes – Enhanced Two-Photon Imaging
TPCs dyes are tailored for two-photon fluorescence bioimaging, addressing the challenge of polar fluorescence quenching.
- Anti-solvation effect: Prevents fluorescence quenching in polar environments
- Strong fluorescence & large two-photon absorption cross-section
- Enhanced imaging contrast in aqueous solutions
| Product name | CAS | Item number |
|---|---|---|
| TPC3, 95% | 2232881-29-5 | 9332545 |
| TPC7, 95% | 2231756-79-7 | 9332546 |
6. TPQLs Fluorescent Dyes – Precision Two-Photon Imaging
Engineered for high-accuracy bioimaging, TPQLs dyes offer:
- High fluorescence quantum yield
- Good solvent insensitivity, minimizing false signals
- Improved imaging signal-to-background ratio, ensuring reliable detection in complex environments
| Product name | CAS | Item number |
|---|---|---|
| TPQL1, 95% | 2766877-57-8 | 9332553 |
| TPQL2, 95% | 2766877-58-9 | 9332554 |
7. SBFs Fluorescent Dye – Full-Spectrum, Color-Tunable, & Environmentally Insensitive
This single-benzene ring dye is highly versatile, suitable for biological imaging and detection.
- High fluorescence quantum yield & large Stokes shift
- Stable across different environments
- Easily modified into diverse fluorescent probes for imaging, labeling, and detection of endogenous substances
| Product name | CAS | Item number |
|---|---|---|
| SBF2, 95% | 2378641-53-1 | 9332547 |
| SBF3, 95% | 2378643-51-5 | 9332548 |
| SBF4, 95% | 2378641-02-0 | 9332549 |
| SBF5, 95% | 2378641-02-0 | 956384 |
| SBF6, 95% | 2378627-17-7 | 9332550 |
| SBF7, 95% | 2378643-51-5 | 947353 |
| SBF8, 95% | 2378641-69-9 | 9332551 |
| Mito-SBF, 95% | 2409179-17-3 | 9332552 |
| HClO-SBF, 95% | 2378640-54-9 | 9332826 |
8. DQF Fluorescent Dye – Rhodamine-Based with Large Stokes Shift
Compared to traditional rhodamine dyes, DQF fluorescent dyes exhibit:
- Larger Stokes shift, reducing background noise
- Improved photostability for prolonged imaging sessions
- Optimized for high signal-to-noise imaging in cells, tissues, and live organisms
| Product name | CAS | Item number |
|---|---|---|
| DQF-560, 95% | / | 9332535 |
| DQF-565, 95% | / | 9332536 |
| DQF-584, 95% | / | 9332537 |
向阳 翟
