Ligands can bond with metal central atoms through coordination or covalent bonds, directly affecting the chemical environment around metal atoms, thereby improving reaction conditions, catalytic activity and conversion rates. So far, scientists have developed Thousands of chiral ligands. Among them, chiral oxazoline ligands have the advantages of diverse structures, easy access to chiral sources, and good asymmetric induction properties. They have become a research hotspot in asymmetric catalysis and are widely used in Diels-Alder reactions, Mannich reactions, Heck reactions, and Henry reactions. reaction and other asymmetric synthesis reactions. In recent years, the research group of Professor Ye Longwu of Xiamen University has developed a new type of highly efficient bidentate oxazoline chiral ligands that can complex with transition metals such as copper and zinc to catalyze a series of asymmetric reactions. Compared with phenyl-substituted BOX ligands, this type of ligand has greater steric hindrance and is expected to exhibit higher enantioselectivity in certain asymmetric catalytic reactions.
Bailingwei can provide high-efficiency bidentate oxazoline chiral ligands developed by the research group of Professor Ye Longwu of Xiamen University, and can provide thousands of asymmetric synthesis supporting products:

Complete range: covering different series such as chiral ligands, metal catalysts, organic molecular catalysts, chiral building blocks, chiral prosthetic groups, chiral reagents, chiral separation reagents, etc.;
Product frontier: It can provide new chiral ligands and catalysts that can be transformed into the scientific research results of experts and scholars in this field;
Quality assurance: high purity, strict quality control, and stable batch quality.

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metal catalyst
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Bis(1,5-cyclooctadiene)nickel(0), 98% 1295-35-8 112324
Palladium(II) acetate, 47.5% Pd 3375-31-3 234582
Tris(N,N-bis(trimethylsilyl)amide)yttrium(III), min. 98% (99.9%-Y) (REO) 41836-28-6 39-1500

 

Organic small molecule catalyst
Product name CAS Item number
(R)-3,3'-Bis(2,4,6-triisopropylphenyl)-1,1'-binaphthyl-2,2'-diyl hydrogenphosphate, 98%, ee: ≥99% 791616-63-2 807455
(11bR)-2,6-Bis(3,5-bis(trifluoromethyl)phenyl)-8,9,10,11,12,13,14,15-octahydro-4-hydroxy-4-oxide-dinaphtho(2,1-d:1',2'-f)(1,3,2)dioxaphosphepin, 98%, ee: 99% 1011465-24-9 2463939
(11bR)-4-Hydroxy-2,6-bis(4-nitrophenyl)-4-oxide-dinaphtho(2,1-d:1',2'-f)(1,3,2)dioxaphosphepin, 98%, ee: 99% 695162-89-1 1809252

 

Chiral prosthetic groups, reagents and resolving reagents
Product name CAS Item number
(-)-B-Chlorodiisopinocampheylborane, 60 wt.% solution in heptane, ca.1.7 M, J&KSeal 85116-37-6 593715
(S)-(+)-α-Methoxy-α-(trifluoromethyl)phenylacetyl chloride, 99% 20445-33-4 191106
L-(+)-Tartaric acid, 99.5% 87-69-4 245105

 

chiral building blocks
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(+)-Diethyl L-tartrate, 99% 87-91-2 116068
Quinine, 97%, anhydrous 130-95-0 348554
L-Glutamic acid, 99% 56-86-0 288636

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Organometallic reagents
Product name CAS Item number
2-Methyl-1-propenylmagnesium bromide, 0.5 M solution in THF, J&KSeal 38614-36-7 611972
Phenylmagnesium bromide, 2.9 M solution in 2-MeTHF, J&KSeal 100-58-3 968141
(Trimethylsilyl)methyllithium, 0.55 M solution in hexanes, J&KSeal 1822-00-0 903940

 

Synthetic reagents
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N,N-Diisopropylethylamine, 99.5% 7087-68-5 203402
Titanium(IV) isopropoxide, 98% 546-68-9 162947
Tris(trimethylsilyl)silane, 97% 1873-77-4 197987

 

General product
Product name CAS Item number
1,4-Dioxane, 99.5%, SuperDry, with molecular sieves, stabilized with BHT, J&Kseal, Peroxides:≤0.03% 123-91-1 972869
Dimethyl sulfoxide-d6, N/A, 99.8 atom%D, contains 0.03% v/v TMS 2206-27-1 182473
Digital stainless steel hotplate magnetic stirrer, with heating, heating temperature range: RT 340℃, power 550 W N/A 1122416

 

By 向阳 翟

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