Chromones and their derivatives are ubiquitous in natural products. This heterocyclic compound shows a variety of pharmacological properties and is one of the important frameworks for drug development. So far, scientists have synthesized a variety of functionalized chromones, especially C3-functionalized chromones. Studies have shown that 3-aminochromone has biological activities such as anti-inflammatory, anticonvulsant, anti-rheumatic and anti-mutagenic. However, the synthesis method of C3-amino-substituted chromone derivatives usually has complex steps and even requires the use of toxic reagents, and its application is subject to certain restrictions. limit. Professor Yang Hua from Central South University has developed a new amino radical precursor (Product No.: 9200608), which can aminate various heterocyclic rings under visible light driving conditions. This amination reagent has been successfully used to synthesize 3-aminochromone. The reaction conditions are mild, which is conducive to the rapid construction and expansion of the chromone skeleton. The products obtained by amination can be used for further functionalization, and many molecules with potential biological activity can be obtained [1 ][1]
Bailingwei exclusively provides new amination reagents developed by Professor Yang Hua of Central South University, which are stable in nature and can be stored at room temperature.
product information
Product name:
tert-Butyl (perchloropyridin-4-yl)oxycarbamate
CAS：2591503-08-9
References
向阳 翟
