High-fidelity in vivo fluorescence monitoring of physiological processes is crucial in disease diagnosis and biological research, but it faces extreme challenges due to aggregation-induced quenching (ACQ) and short-wavelength fluorescence. The development of high-performance, long-wavelength aggregation-induced emission (AIE) fluorophores has placed higher demands on precise optical bioimaging.Chromophore-quinoline-malononitrile (quinolinenitrile, QM) is a...

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FM series fluorescent dyes include FM 1-43, FM 2-10, FM 5-95, and FM 4-64. They are a type of lipophilic styrene fluorescent dyes that are non-toxic to cells and are mainly used for living cell membranes, especially plant samples. Specific labeling of cell membranes, tracer imaging of neuronal cells, and...

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Conventional methods for attaching single-stranded DNA (ssDNA) to IgG antibodies often face several challenges. These include high costs associated with ssDNA modification, low coupling efficiency, complex reaction and purification processes, and difficulties in controlling the stoichiometry between ssDNA and IgG.  Professor Hang Xing from Hunan University developed the "AND Linker”,...

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The difference between spotting capillary and sealed melting point capillary1. Production methodThe production of spotting capillaries is generally made by tangentially connecting glass capillaries and pipettes. The production process mainly includes three steps: tip treatment, tube wall protection and filling. Among them, the treatment of the tube tip is the...

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How to Choose a Syringe Filter The primary purpose of a syringe filter is to filter liquids, removing particles, precipitates, microorganisms, etc. They find widespread applications in fields such as biology, chemistry, environmental science, medicine, and pharmaceuticals, owing to their excellent filtration efficiency, convenience, and effectiveness. However, selecting the right...

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L-Aspartic Acid: Synthesis and Applications L-Aspartic Acid finds widespread applications in medicine, food, and the chemical industry. In the field of medicine, it is employed for the treatment of heart diseases, liver disorders, hypertension, and possesses fatigue prevention and recovery properties. It is combined with various amino acids to formulate...

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