Fluorine is an important non-metal element. Due to its unique electronegativity, electronic effect and steric hindrance effect, fluorine atoms are often introduced into drugs to regulate drug metabolism pathways, improve metabolic stability and permeability, etc., and have been More than 20% of drugs and pesticides on the market contain one or more fluorine atoms. The green and efficient synthesis of fluoride has become a research hotspot in fluorine chemistry. Professor Bi Xihe of Northeast Normal University developed two new solid fluorination reagents - trifluoroacetaldehyde N-trifluoromethylbenzenesulfonylhydrazone reagent (TFHZ-Tfs) and N-(o-trifluoromethyl)dihydrazone Fluoroacetaldehyde benzenesulfonylhydrazone reagent (DFHZ-Tfs), both of which can be used as precursors of gas fluorination reagents trifluoromethyldiazomethane and difluoromethyldiazomethane, quantitatively control their generation rate and adjust as needed The degree of reaction makes it safer to store and use.

Bailingwei can provide reagents required for the synthesis and transformation methodology research of a variety of fluorine-containing compounds:

Full range: covering fluorinated reagents, fluorinated building blocks, catalysts and ligands, alkynes, boron-containing compounds, organometallic reagents, synthetic reagents, etc. We also provide supporting inorganic reagents, ultra-dry solvents, nuclear magnetic solvents and common instrument consumables. ;
New products: new fluorinated reagents that can be used to transform the scientific research results of scientists in this field;
Quality assurance: high purity, strict quality control, and stable batch quality.

Recommended products

Product name CAS Item number
Difluoroacetaldehyde N-triftosylhydrazone, 98% 2245235-35-0 9171852
TFHZ-Tfs, 98% 2236129-81-8 9025326

 

 含氟砌块
Product name CAS Item number
(Trifluoromethoxy)benzene, 99% 456-55-3 237816
Fluorobenzene, 99% 462-06-6 514999
1,1,1-Trifluoro-3-phenyl-2-propanone, 97% 350-92-5 503875

 

 催化剂和配体
Product name CAS Item number
Chloro(1,5-cyclooctadiene)rhodium(I) dimer, 98% 12092-47-6 500156
Nickel(II) bromide, dimethoxyethane adduct, min. 97% 28923-39-9 28-1145
Tris(4-fluorophenyl)phosphine, 98% 18437-78-0 342295

 

 光催化剂
Product name CAS Item number
(2,2'-Bipyridine)bis[2-pyridinyl-kN)phenyl-kC]iridium(III) hexafluorophosphate, 99% 106294-60-4 77-0465
Eosin Y 15086-94-9 985235
Rhodamine B, 96% 81-88-9 603231

 

 炔烃
Product name CAS Item number
Cyclohexylacetylene, 98% 931-48-6 C38079
5-Decyne, 98% 1942-46-7 995332
3-Methyl-1-butyne, 95% 598-23-2 796593

 

 含硼化合物
Product name CAS Item number
4-Aminophenylboronic acid pinacol ester, 98% 214360-73-3 205857
Phenylboronic acid, 99% 98-80-6 390913

 

 有机金属试剂
Product name CAS Item number
Isopropylmagnesium bromide, 2.0 M solution in 2-MeTHF, J&KSeal 920-39-8 967342
Lithium diisopropylamide, 2.0 M solution in THF/n-heptane/ethylbenzene (22%/35%/14%), J&KSeal 4111-54-0 982171
Phenylmagnesium bromide, 2.9 M solution in 2-MeTHF, J&KSeal 100-58-3 968141

 

 合成试剂
Product name CAS Item number
Diisobutylaluminum hydride, 1.0 M solution in hexanes, J&Kseal, Colorless 1191-15-7 997665
Iodomethane, 99%, stabilized with copper chip 74-88-4 395069
Triethylamine, 99.7%, HPLC grade 121-44-8 983728

 

 通用产品
Product name CAS Item number
Cerium(III) chloride, 99.9%, anhydrous 7790-86-5 125652
1,4-Dioxane, 99.5%, SuperDry, with molecular sieves, stabilized with BHT, J&Kseal, Peroxides:≤0.03% 123-91-1 972869
Magnetic stir bar, PTFE-coated, egg-shaped, A100 (6*10mm), 5 pcs/pack / 1482821

 

By 向阳 翟

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