The basic building blocks of biomimetic homopolypeptides are protected or unprotected glutamic acid or lysine residues, which are obtained through ring-opening polymerization of cyclic amino acid anhydrides. They can be used in the field of biomedicine as drug delivery, gene delivery carriers or degradable biomimetic medical materials [1-2]. They can also be used as polymer building blocks in the synthesis, modification and modification of various functional materials, for example, Modify polymer membrane materials and nanomaterials to control their properties.
J&K exclusively sells the homopolypeptide products of Professor Bai Yugang of Hunan University.
The product advantages:
- Molecular weight can be controlled and customized;
- Narrow molecular weight distribution (PDI<1.2);
- The repeating unit chirality can be customized.
Figure 1 Product structure diagram
Product list
| Product name | CAS | Item number |
|---|---|---|
|
Poly-γ-benzyl-L-glutamate, 95%, average Mn 22,000 |
25014-27-1 |
100056 |
|
Poly(L-glutamic acid), 95%, average Mn 13,000 g/mol |
25513-46-6 |
141991 |
|
Poly(Nepsilon-carbobenzoxy-L-lysine), 95%, average Mn 26,000 g/mol |
25931-47-9 |
316758 |
|
Poly-(L-lysine), 95%, average Mn 13,000 g/mol |
25104-18-1 |
1168079 |
References
- Nathan P. Gabrielson, Hua L, Lichen Y, et al. Reactive and Bioactive Cationic a-Helical Polypeptide Template for Nonviral Gene Delivery** [J][J]. J. Am. Chem. Soc. 2016, 138, 9498−9507.
向阳 翟
