Fluorine is an important non-metal element. Due to its unique electronegativity, electronic effect and steric hindrance effect, fluorine atoms are often introduced into drugs to regulate drug metabolism pathways, improve metabolic stability and permeability, etc., and have been More than 20% of drugs and pesticides on the market contain one or more fluorine atoms. The green and efficient synthesis of fluoride has become a research hotspot in fluorine chemistry. Researcher Hu Jinbo introduced two new fluorination reagents - sodium difluoromethylsulfinate and sodium monofluoromethylsulfinate. Both are colorless solids with stable properties and can react with appropriate oxidants. Alkenes, heteroatoms, isocyanates, aromatic heterocycles, cyclopropanes, etc. undergo free radical reactions to generate corresponding products containing CF2H or CH2F, which is easy to operate.
J&K Scientific can provide reagents required for the synthesis and transformation methodology research of a variety of fluorine-containing compounds:
Full range: covering fluorination reagents, fluorine-containing building blocks, catalysts and ligands, alkynes, boron-containing compounds, organometallic reagents, synthetic reagents, etc. We also provide supporting inorganic reagents, ultra-dry solvents, nuclear magnetic solvents and common instrument consumables. ;
New products: new fluorinated reagents that can be used to transform the scientific research results of scientists in this field;
Quality assurance: high purity, strict quality control, and stable batch quality.
Recommended products
Product name | CAS | Item number |
---|---|---|
Sodium difluoromethanesulfinate, 98% | 275818-95-6 | 2465675 |
Sodium fluoromethanesulfinate, 98% | 1661836-10-7 | 2465682 |
Fluorine building blocks
Product name | CAS | Item number |
---|---|---|
Benzotrifluoride, 99%, SuperDry, water≤10 ppm, J&KSeal | 98-08-8 |
350291 Hazardous chemicals |
3-Fluorosalicylaldehyde, 99% | 394-50-3 | 107326 |
Pentafluorobenzene, 99% | 363-72-4 | 446634 |
Catalysts and ligands
Product name | CAS | Item number |
---|---|---|
Bis(1,5-cyclooctadiene)nickel(0), 98% | 1295-35-8 | 112324 |
Copper(I) iodide, 98% | 7681-65-4 | 988790 |
Tetrakis[(R)-(-)-][(1R)-1-(4-bromophenyl)-2,2-diphenylcyclopropanecarboxylato]dirhodium(II) Rh2(R-BTPCP)4 | 1345974-62-0 | 45-2080 |
Photocatalyst
Product name | CAS | Item number |
---|---|---|
Eosin Y | 15086-94-9 | 985235 |
Rhodamine 6G, indicator | 989-38-8 | 151183 |
Tris(2-phenylpyridine)iridium, 99%, for synthesis | 94928-86-6 | 997766 |
Alkynes
Product name | CAS | Item number |
---|---|---|
5-Decyne, 98% | 1942-46-7 | 995332 |
3-Methyl-1-butyne, 95% | 598-23-2 | 796593 |
1-Phenyl-1-butyne, 97% | 622-76-4 | 920562 |
Boron compounds
Product name | CAS | Item number |
---|---|---|
4-Formylphenylboronic acid, 97% | 87199-17-5 | 277581 |
Phenylboronic acid, 99% | 98-80-6 | 390913 |
Organometallic reagents
Product name | CAS | Item number |
---|---|---|
n-Butyllithium, 1.6 M solution in hexanes, J&KSeal | 109-72-8 | 274232 |
Lithium bis(trimethylsilyl)amide, 1.0 M solution in THF, J&KSeal | 4039-32-1 | 932250 |
Phenyllithium, 1.5-1.7M in cyclohexane/ether, 70:30%, packaged under Argon in resealable ChemSeal^t bottles | 591-51-5 | 043259 |
Synthetic reagents
Product name | CAS | Item number |
---|---|---|
Chlorotrimethylsilane, 98%, J&Kseal | 75-77-4 |
932010 Hazardous chemicals |
Iodomethane, 99%, stabilized with copper chip | 74-88-4 |
395069 Hazardous chemicals |
Sodium iodide, 99%, for analysis | 7681-82-5 | 191037 |
General product
Product name | CAS | Item number |
---|---|---|
Benzene, 99.7%, HPLC grade | 71-43-2 |
335612 Hazardous chemicals |
Dichloromethane-d2, 99.8 atom%D | 1665-00-5 | 334919 |
Iridium(III) chloride hydrate, 50 - 58% Ir | 14996-61-3 | 110534 |