Coumarin Compounds: Versatile Fluorescent Chromophores for Advanced Research

Coumarin compounds are highly versatile fluorescent and laser dyes with exceptional performance characteristics. As fluorescent chromophores, they have remained a focal point in the research and development of fluorescent probes. These compounds are widely used for synthesizing coumarin derivatives and optical probes capable of detecting metal ions like Hg²⁺ and anions such as HSO₃⁻ (Figures 1-2).

Figure 1 Fluorescent Hg2+ probe based on desulfurization reaction[1]

Figure 2 Multi-channel fluorescent probes based on coumarin and ethylenediamine have "turn-on" properties and can identify Al3+, Hg2+ and ClO-, with maximum emission wavelengths of 459nm, 485nm and 504nm respectively[2]

J&K Scientific offers high-quality 7-(diethylamino)coumarin, synthesized and developed by Professor Wang Qin, to meet the demands of cutting-edge research.

Advantages of 7-(Diethylamino)coumarin

Large Stokes Shift:

• Reduces spectral overlap, enhancing fluorescence detection sensitivity.

Low Background Interference:

• Improves signal-to-noise ratio for accurate measurements.

Good Photostability:

• Ensures consistent and reliable fluorescence performance over extended periods.

These features make 7-(diethylamino)coumarin an excellent choice for applications in fluorescence imaging and probe development.

Applications of Coumarin-Based Probes

Metal Ion Detection:

• Effective in the selective detection of metal ions like Hg²⁺.

Anion Sensing:

• Used in detecting specific anions such as HSO₃⁻, expanding its use in environmental and biochemical research.

Fluorescent Chromophores:

• Integral to the development of innovative fluorescent probes.

Professor Wang Qin, from the School of Chemistry and Environmental Sciences at Shaanxi University of Science and Technology, specializes in nanofluorescent probes. With a strong focus on both the construction and application of these probes, he has published numerous papers in SCI-indexed journals, including nine as the first author. Additionally, Professor Wang has contributed to two National Natural Science Foundation projects, advancing the field of fluorescent probe research.

J&K Scientific provides premium 7-(diethylamino)coumarin, ensuring exceptional quality and performance for researchers worldwide. Whether for fluorescent probe development or advanced molecular sensing, J&K Scientific supports innovation in fluorescence-based research.

References