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Sku 44-0166-50MG
STREM
Technical Notes:
1.Biaryl bisphosphine ligand. The Ha-BINAP ligand, as the ruthenium complex, catalyzes hydrogenation of unsaturated carboxylic acids to a higher ee than does BINAP. (Ref. 1,2)
2.The ruthenium catalyzed hydrogenation of aryl propenoic acid to produce the drug lbuprofen.
References:
1. Org. Chem.. 1996, 61. 5510.
2. Topics Organometal. Chem. 2004, 6, 63 (review).